Amiodarone causes prolonged thyroid dysfunction, with reversible hypothyroidism often preceding late-onset thyrotoxicosis, necessitating long-term thyroid monitoring post-withdrawal.
Long-term thyroid function monitoring is necessary even after amiodarone withdrawal due to the drug's prolonged metabolic effects and risk of sequential thyroid dysfunction.
Absolute Event Rate: 0% vs 0%
Our report underscores three key points: (1) the prolonged metabolic effects of iodine load and tissue toxicity even after amiodarone cessation, (2) the possibility of reversible amiodarone-induced hypothyroidism preceding subsequent thyrotoxicosis, and (3) the need for long-term thyroid function monitoring, even after amiodarone withdrawal.
Soares et al. (Sun,) reported a other. Amiodarone causes prolonged thyroid dysfunction, with reversible hypothyroidism often preceding late-onset thyrotoxicosis, necessitating long-term thyroid monitoring post-withdrawal.