Integrative Analysis of Bacterial Diversity in Patients with Type 2 Diabetes Mellitus and Periodontitis Using a Case-Control Microbiome Approach

Key Points

• The research aims to investigate the relationship between bacterial diversity and type 2 diabetes mellitus (T2DM) in the context of periodontitis.
• Conducted a case-control microbiome analysis.
• Analyzed salivary samples from patients with T2DM and periodontitis.
• Identified bacterial taxa and functional pathways.
• Detected significant shifts in salivary microbial composition in T2DM patients.
• Linked specific taxa to the presence of periodontitis.
• Predicted functional pathways associated with altered microbial diversity.

Abstract