Substituted Ureas and Their Analogues Containing Framework Fragments. III. Features of the Synthesis of Monoimines Based on Camphor and Aliphatic Diamines

Key Points

• The aim is to selectively synthesize monoimines from camphor and various aliphatic diamines.
• Selected three diamines: 1,2-diaminoethane, 1,3-diaminopropane, and 1,6-diaminohexane.
• Conducted comparative analysis of synthesis selectivity.
• Utilized zinc carboxylates as catalysts in the reaction.
• Achieved over 90% selectivity with 1,6-diaminohexane at a 5-fold molar excess.
• Selectivity remained high for 1,3-diaminopropane but dropped to 77.4% for 1,2-diaminoethane.
• The selectivity patterns were explained through the reaction mechanism.