What question did this study set out to answer?

To explore the evolving role of transplant oncology in treating primary liver cancer and metastatic disease.

February 28, 2026

The rise of transplant oncology in primary liver cancer and metastatic disease

Key Points

To explore the evolving role of transplant oncology in treating primary liver cancer and metastatic disease.
Review of current transplantation protocols for liver malignancies
Analysis of evidence supporting expanded indications for liver transplantation
Discussion of downstaging techniques and immunosuppression strategies
Evidence supports liver transplantation in selected patients with liver malignancies
Optimized downstaging techniques improve transplant eligibility
Innovative donor strategies enhance the availability of suitable organs

Abstract

Transplant oncology reshapes the therapeutic landscape of liver malignancies, with growing evidence supporting liver transplantation in carefully selected patients beyond traditional indications. Optimized downstaging, innovative donor strategies, and tailored immunosuppression are pivotal for safe expansion. Continued collaboration between the transplant and oncology disciplines, along with prospective trials, is essential to further define standardized protocols and solidify transplantation as a cornerstone of multidisciplinary cancer care.

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Discussion

Authors

Jérémy Meyer

David Malka

TM Wong

Journals

Hepatology

Actions

Institutions

University of Toronto

Mayo Clinic

University of Hong Kong

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

The rise of transplant oncology in primary liver cancer and metastatic disease

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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