What question did this study set out to answer?

This study investigates the relationship between transient global amnesia and high-grade jugular vein stenosis.

February 28, 2026Open Access

Transient Global Amnesia and High-Grade Styloidogenic Jugular Vein Stenosis

Key Points

This study investigates the relationship between transient global amnesia and high-grade jugular vein stenosis.
Conducted a case-control study comparing patients with transient global amnesia to healthy participants.
Assessed the severity of stenosis in the jugular vein using MRI.
Examined the internal jugular veins for small-caliber presentations.
Found a significant association between transient global amnesia and high-grade jugular vein stenosis.
Identified an approximately 70% stenosis threshold in right-sided or bilateral internal jugular veins as a potential diagnostic marker.

Abstract

In this case-control study of patients with TGA vs healthy participants, TGA was associated with high-grade SJVC in the presence of small-caliber IJVs, with an approximately 70% right-sided or bilateral IJV stenosis threshold emerging as a promising imaging covariate for supporting the clinical diagnosis of TGA. These results suggest that MRI assessment of SJVC severity may improve diagnostic accuracy in atypical TGA presentations.

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Cite this study

Muneer et al. (Thu,) studied this question.

www.synapsesocial.com/papers/69a287a00a974eb0d3c0383c — DOI: https://doi.org/10.1001/jamanetworkopen.2026.0065

Authors

Mohamed S. Muneer

Kellen Vo Vu

Siddhant Suri Dhawan

Journals

JAMA Network Open

Actions

Institutions

Stanford University

Cornell University

Weill Cornell Medicine

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Transient Global Amnesia and High-Grade Styloidogenic Jugular Vein Stenosis

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion