A Case of Concurrent Pancreatic Adenosquamous Carcinoma and Primary Lung Squamous Cell Carcinoma Successfully Treated with Radical Resection Following Response to FOLFIRINOX Therapy

Key Points

• The study aims to present a rare case of concurrent pancreatic and lung cancers and their successful management.
• Initial diagnosis of abdominal pain leading to CT scans revealing both tumor types.
• Administration of FOLFIRINOX chemotherapy for five months to shrink both tumors.
• Performing subtotal stomach-preserving pancreaticoduodenectomy followed by right upper lobectomy 46 days later.
• Confirmation of both tumors as adenosquamous carcinoma of the pancreas and squamous cell carcinoma of the lung post-surgery.
• Both tumors were successfully reduced in size and achieved R0 resection.
• Post-operative evaluations indicated higher activity of lung cancer compared to pancreatic cancer, leading to tailored chemotherapy after surgery.
• As of 16 months post-lung surgery, the patient remains free from recurrence.

Abstract