From ideal respiratory health to chronic lung disease: indicators of impaired respiratory health.

Key Points

• The aim is to identify the shared biologic mechanisms that influence chronic lung diseases and improve prevention strategies.
• Utilized a multi-omic approach integrating clinical, physiologic, imaging, and molecular data.
• Evaluated individuals at increased risk for chronic respiratory disease.
• Proposed prospective evaluation to assess the impact of preventative strategies.
• Identified key indicators linking ideal respiratory health to chronic lung disease.
• Highlight the importance of integrating diverse data types for effective prevention.
• Found that a more holistic framework is needed for respiratory health evaluation.

Abstract