Introduction: Dental caries, etiologically is a multifactorial disease because of both bacterial acid production along with the buffering action from saliva and the surrounding surface of the tooth structure earlier visible as White Spot Lesions (WSLs). Remineralization is the process whereby calcium ions and phosphate ions are supplied from an external source to the tooth to promote ion deposition into crystal voids. Evidence shows that early caries lesions can be mineralized in-vitro and in-vivo, with fluoride as one of the most significant agents for promoting remineralization. Aim: To compare and evaluate the of remineralizing potential of Enafix, Clinpro5000 and GC Tooth Mousse on artificially demineralized human enamel- An in vitro study. Materials and Methods: 40 enamel samples were divided into 4 groups. Group A: CaSP (Enafix); Group B: Tricalcium phosphate (Clinpro5000); Group C: CPP-ACP (GC Tooth mousse) and Group D (control) containing dentifrice. All teeth were subjected to demineralization for 24hours followed by remineralization with respective dentifrice for 30 days and the VHN was assessed. Results: The result of this study concludes that surface microhardness of enamel decreased after demineralization procedure and increased after application of all the remineralizing agents. The highest increase was seen in group tested with fTCP followed by CPP-ACP and least for CaSP. The values for all the three groups were higher than the control so we can conclude that all the agents can be used as remineralizing agent with f-TCP being the best among the three. Conclusion: All remineralizing agents showed improved surface remineralization. However, Tri-calcium phospahte showed a better potential for remineralization compared to CPP-ACP and CaSP.
2Dr. Aswathi K. 1*Dr. Hajira Sahal Sultan (2026) studied this question.