Assessment of perioperative bleeding in pediatric osteogenesis imperfecta patients undergoing orthopedic surgeries: A single-center study

Background “Osteogenesis imperfecta (OI)” is a heterogeneous group of inherited disorders involving collagen type I with a 10–30% incidence of bleeding diathesis placing these individuals at an increased risk of bleeding. Our study aims to ascertain the risk factors that increase the propensity of perioperative blood transfusions in pediatric population. Methods A single center retrospective observational study of patients aged 2 = 0.076). Conclusion Our study inferred that the fall in hemoglobin was significant postoperatively in OI patients and was associated with younger age, type III OI, and multiple osteotomies. Before performing orthopedic surgeries on patients with OI, surgeons might consider the latter risk factors to explore therapeutic options aimed at reducing hemorrhage and improving outcomes.