This work formulates a hypothesis regarding the possibility of influencing the processes of aging, recovery, and treatment of the organism through modifications of the energetic conditions underlying the existence of living matter. In contrast to traditional biochemical and physiological approaches, a proposed physical–energetic level of influence is considered, associated with changes in energetic conditions at the atomic level of organismal functioning. Within the proposed model, it is hypothesized that a phase of temporary energetic limitation, followed by a phase of controlled restoration of energetic conditions, may lead to a reorganization of biological processes. According to this hypothesis, such reorganization may create conditions conducive to tissue regeneration and the recovery of impaired functional properties of the organism. It is further suggested that the restoration of energetic conditions may activate intrinsic regulatory information within biological systems, facilitating the return of specific structures and functions to an earlier functional state. On this basis, a conceptual two-phase medical–engineering model is proposed, comprising a phase of artificial energetic limitation and a subsequent phase of energetic restoration. A conceptual experimental setup is described that may allow for a temporary modification of the energetic conditions of organismal functioning relative to its normal physiological state. This work is hypothesis-forming in nature and aims to raise the question of the fundamental testability of controlling the energetic regime of living systems and the potential role of such control in processes of aging, recovery, and treatment.
Yevgen Ivashura (Sat,) studied this question.