Gut T cell-microbiota crosstalk orchestrates antibacterial immunity and mucosal homeostasis in teleost

Key Points

• The research investigates how teleost T cells interact with gut microbiota to regulate immunity and homeostasis.
• Examined bidirectional interactions between T cells and gut microbiota in teleost fish.
• Analyzed roles of T cells in antimicrobial defense and maintenance of mucosal homeostasis.
• Teleost T cells engage with gut microbiota to enhance antibacterial defense.
• T cell-microbiota cooperation contributes to maintaining mucosal health.
• Findings suggest these interactions have ancient evolutionary origins.

Abstract