Patient-derived lung organoids from bronchoalveolar lavage capture epithelial heterogeneity and disease biology in bronchopulmonary dysplasia

Key Points

• Capturing epithelial heterogeneity, patient-derived lung organoids provide insights into bronchopulmonary dysplasia.
• The analysis demonstrates the potential of bronchoalveolar lavage samples to inform on disease biology and pathology.
• Using lung organoids, the study reveals distinct cellular responses associated with bronchopulmonary dysplasia.
• This work highlights the need for deeper exploration of organoid technology in understanding complex lung diseases.