Corneal Stromal Thinning and Posterior Irregularity After DMEK: Clinical Observations and Biophysical Hypotheses

Key Points

• Postoperative stromal thinning correlates with reduced corneal thickness and hyperopic shift after DMEK.
• Greater reductions in corneal thickness are linked to preoperative stromal ripples and endothelial recovery.
• Observations indicate that stromal remodeling is influenced by the biomechanical status of the cornea, highlighting its role.
• The study suggests potential implications of keratocyte loss and osmotic imbalance in corneal health post-surgery.

Abstract