The effect of Indigenous American genomic ancestry on type 2 diabetes in Mexico: an analysis of 134 548 individuals from the Mexico City Prospective Study

Key Points

• Type 2 diabetes incidence is influenced by Indigenous American genomic ancestry in Mexico, revealing significant findings for healthcare.
• A sample of 134,548 individuals highlights that genomic ancestry correlates with varying diabetes risk levels.
• Epidemiological analysis across diverse regions in Mexico emphasizes the importance of cultural and genetic factors.
• Understanding these ancestral links may help tailor diabetes prevention strategies, addressing specific genetic risk factors.

Abstract