miR-4687-5p promotes the progression of diabetic retinopathy by targeting SIRT2 to mediate inflammatory responses

Key Points

• Progression of diabetic retinopathy is promoted by miR-4687-5p targeting SIRT2, enhancing inflammation.
• The findings suggest that miR-4687-5p could serve as a valuable biomarker for early detection of diabetic retinopathy.
• Analysis indicates the manipulation of miR-4687-5p may open new avenues for therapeutic interventions in diabetic retinopathy.
• Highlighting this pathway opens opportunities for targeted treatments to correct inflammatory responses.

Abstract