March 3, 2026Open Access

Structural MRI Biomarkers of Intracranial Pressure in IIH: Linking Optic Nerve Sheath, Pituitary Morphology, and Hormonal Changes

Key Points

Intracranial pressure potentially interacts with endocrine markers and structural MRI measures, indicating important connections.
Key findings suggest cautious interpretation due to limited sample size despite notable structural MRI associations.
Exploratory assessment utilizing structural MRI markers and hormonal analysis across variable endocrine parameters was conducted.
Further research is needed to validate whether these endocrine MRI associations are clinically relevant, emphasizing the need for larger studies.

Abstract

Our exploratory findings suggest potential interactions between ICP, endocrine markers, and structural MRI measures. However, due to the limited sample size and variability in endocrine parameters, the results should be interpreted cautiously and considered hypothesis generating rather than clinically directive. Larger studies are needed to determine whether endocrine MRI associations hold true and whether they have diagnostic or clinical relevance.

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Authors

Zeynep Bendella

Barbara Daria Wichtmann

Ralf Clauberg

Journals

Clinical Neuroradiology

Actions

Institutions

University of Bonn

Heinrich Heine University Düsseldorf

Forschungszentrum Jülich

References and Citations

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Building similarity graph...

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Structural MRI Biomarkers of Intracranial Pressure in IIH: Linking Optic Nerve Sheath, Pituitary Morphology, and Hormonal Changes

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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