March 3, 2026Open Access

Characteristics and Outcomes of Adults Hospitalized With Childhood-Onset Complex Chronic Conditions

Key Points

Young adults with childhood-onset complex chronic conditions experienced longer acute care hospitalizations, accounting for 10.7% of total bed-days.
Compared to other young adults, this group had more rehospitalizations, indicating a need for focused interventions.
The study highlights the limitations of the Charlson Comorbidity Index for capturing comorbidities in this unique population.
Implications suggest prioritizing care measures could enhance health outcomes for these individuals.

Abstract

In this cohort study, young adults with 4Cs had longer acute care medical hospitalizations, accounting for 10.7% of all young adult hospital bed-days, and more rehospitalizations than other young adults. The results suggest that this population should be prioritized for targeted measures to reduce inpatient stays and improve care. The Charlson Comorbidity Index may be of limited utility for capturing comorbidities in this population.

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Discussion

Authors

Sarah Malecki

Trong Shen

Anne Löffler

Journals

JAMA Network Open

Actions

Institutions

University of Toronto

Hospital for Sick Children

University Health Network

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Characteristics and Outcomes of Adults Hospitalized With Childhood-Onset Complex Chronic Conditions

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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