March 3, 2026Open Access

Ischemia modulation via coronary revascularization and effects on the arrhythmic substrate

Key Points

Residual ischemia did not affect the arrhythmic substrate after revascularization, suggesting inherent complexities in management.
Marked heterogeneity in ischemia correlated with the residual arrhythmic substrate, indicating varying patient conditions.

Structured PICO

Does coronary revascularization alter the arrhythmic substrate?

Population

Cohort of patients undergoing coronary revascularization

Intervention

Coronary revascularization

Outcome

Arrhythmic substratesurrogate

Coronary revascularization does not appear to alter the underlying arrhythmic substrate, which correlates strongly with scar burden and residual ischemia.

Abstract

Arrhythmic substrate correlated with scar burden and was unaltered by revascularization in this cohort. There was marked heterogeneity in residual ischemia which correlated with residual arrhythmic substrate. Further work is needed to personalize risk stratification in relation to ischemia reduction and residual arrhythmic risk.

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Discussion

Cite this study

Morgan et al. (Thu,) studied this question.

www.synapsesocial.com/papers/69a75bbfc6e9836116a23a75 — DOI: https://doi.org/10.1016/j.hrthm.2026.01.031

Authors

Holly Morgan

Lubna Choudhury

Marina Strocchi

Journals

Heart Rhythm

Actions

Institutions

Imperial College London

King's College London

Guy's and St Thomas' NHS Foundation Trust

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Ischemia modulation via coronary revascularization and effects on the arrhythmic substrate

Key Points

Structured PICO

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion