Oncologic safety of breast-conserving surgery in node-positive breast cancer: a systematic review and meta-analysis

Key Points

• Breast-conserving surgery with radiation therapy yields similar recurrence outcomes as mastectomy for node-positive breast cancer.
• Findings reveal that BCS with RT provides effective survival rates, emphasizing its role as a patient-centered surgical choice.
• This systematic review involved a meta-analysis assessing the oncologic safety across various populations, with a focus on modern treatment approaches.
• These results may encourage clinical guidelines to reduce unnecessary radical surgeries and promote personalized treatment strategies.

Abstract