The neuroimmune axis: Integrating two systems to decipher itch

Key Points

• Itch is significantly influenced by the neuroimmune axis, highlighting the connection between the nervous system and immune response.
• The immune response plays a vital role in modulating itch, with various molecular pathways involved in this interaction.
• Analysis of immune and nervous system interactions provides insights into itch mechanisms and potential therapeutic targets.
• Understanding the neuroimmune axis may enable new strategies for treating chronic itch conditions effectively.