Water-promoted deconstructive amination of alkenes through single-carbon deletion: access to fully substituted pyrroles

Key Points

• The process allows for the formation of fully substituted pyrroles from dienes using water as a promoter.
• Single-carbon deletion is employed in this sustainable synthetic route without the need for catalysts.
• This approach showcases a novel method for deconstructive amination in organic chemistry.
• The findings suggest potential applications in greener chemical synthesis and sustainability efforts.

Abstract