Layer-by-layer assembly sodium hyaluronate/ε-polylysine-coated Zein nanoparticles enhance the gastrointestinal delivery and anti-inflammatory activity of capsaicinoids

Key Points

• Enhanced gastrointestinal delivery of capsaicinoids leads to improved anti-inflammatory activity.
• The study utilized layer-by-layer assembly techniques in designing the nanoparticles for effective delivery.
• Findings showed a notable increase in the therapeutic potential of capsaicinoids through this nanoparticle system.
• The analysis suggests significant applications in developing anti-inflammatory therapies using dietary compounds.