Transcriptional and epigenetic regulation of Ca2+-signaling genes in hepatitis B-derived hepatocellular carcinoma and their association with the cancer hallmarks

Key Points

• Ca2+-signaling gene regulation may influence cancer hallmarks, affecting tumor growth and progression.
• Key evidence includes the connections between transcriptional and epigenetic modifications and their roles in cancer biology.
• Observational analysis identifies significant links between Ca2+-signaling pathways and hepatocellular carcinoma features.
• Insights gained here may enable novel therapeutic approaches, though further studies are warranted to validate these findings.

Abstract