March 3, 2026Open Access

"In-Silico Evaluation Of BRCA1 Domain 1JM7 Binding Interactions With RAD51 (1N0W) And P53 (1YCR)''

Key Points

Binding interactions of BRCA1, RAD51, and P53 are critical for cellular functions related to DNA repair, and regulation of genes.
Significant binding affinity was predicted, with computational tools allowing for detailed structural analysis.
In-silico evaluations provide insights into molecular interactions, essential for understanding cancer mechanisms.
Findings underscore the importance of BRCA1, RAD51, and P53 interactions in cancer biology; further studies needed for validation.

Abstract

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Authors

Gorle Keerthi

D. Udaya Kumar

Srikakulapu Bhargavi

Journals

INTERNATIONAL JOURNAL OF RESEARCH AND ANALYTICAL REVIEWS

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"In-Silico Evaluation Of BRCA1 Domain 1JM7 Binding Interactions With RAD51 (1N0W) And P53 (1YCR)''

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