Diagnostic Efficiency of Age‐Adjusted PSAD for Prostate Cancer and Clinically Significant Prostate Cancer: Construction and Nomogram Validation

Key Points

• Improved diagnostic efficiency is achieved with age-adjusted PSAD, balancing sensitivity and specificity effectively.
• A-PSAD reduces false positives, leading to fewer unnecessary prostate biopsies and improved outcomes.
• Validation involved constructing and testing a nomogram to enhance personalized screening for prostate cancer.
• The findings support the use of age-adjusted PSAD in clinical settings, promoting better screening practices.

Abstract