March 3, 2026

Re: ‘Risk of dementia following gabapentin prescription in chronic low back pain patients’

Key Points

Causality may be linked to gabapentin prescription and increased dementia risk.
The analysis emphasizes the need for randomized controlled trials to evaluate this relationship effectively.
Establishing a link between gabapentin and cognitive impairment underscores the complexity of medication effects.
Highlighting this potential risk calls for careful consideration in prescribing practices for chronic low back pain.

Abstract

Claiming that gabapentin prescription increases the risk of dementia and cognitive impairment” implies causality. Establishing causality is a central objective of clinical research, and the gold standard for determining causality is the randomized controlled trial (RCT). However, not all questions

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Cite this study

Khan et al. (Wed,) studied this question.

www.synapsesocial.com/papers/69a75c42c6e9836116a24f4e — DOI: https://doi.org/10.1136/rapm-2025-107265

Authors

James Khan

Rhyall William Sinclair Hughes

Tri-Long Nguyen

Journals

Regional Anesthesia & Pain Medicine

Actions

Institutions

University of Copenhagen

Mount Sinai Hospital

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Re: ‘Risk of dementia following gabapentin prescription in chronic low back pain patients’

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion