Incidence and bacterial etiology of acute otitis media in children in the pneumococcal conjugate vaccine era: A systematic literature review and meta-analysis

Key Points

• Acute otitis media incidence rates have changed in the post-vaccination era, indicating new patterns.
• The review highlights bacterial etiology shifts, showing a rise in non-typeable strains post-vaccination.
• Analysis of multiple studies indicates variations based on geographic locations, influencing local treatment guidelines.
• Supports the need for updated vaccination strategies and treatment protocols based on current bacterial profiles.