Is metabolic dysfunction-associated fatty liver disease (MAFLD) associated with a higher prevalence of cardiovascular autonomic neuropathy in patients with type 2 diabetes?
Patients with type 2 diabetes (T2DM)
Presence of metabolic dysfunction-associated fatty liver disease (MAFLD)
Absence of MAFLD
Prevalence of cardiovascular autonomic neuropathy (DCAN)
Screening for MAFLD and high FIB-4 levels in patients with T2DM may help identify those at higher risk for cardiovascular autonomic neuropathy.
MAFLD is independently associated with a higher prevalence of DCAN in patients with T2DM. The risk was further amplified when high FIB-4 index (FIB-4 >1.3) was present among those with MAFLD. Hence, screening for MAFLD and its associated high FIB-4 levels may help identify patients with T2DM at a higher risk of DCAN.
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Rong Peng
Yaoyun Ao
Enni Cen
Frontiers in Endocrinology
SHILAP Revista de lepidopterología
Guangdong Academy of Medical Sciences
Medical Center Hospital
Jiangmen Central Hospital
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Peng et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69a75ceec6e9836116a26374 — DOI: https://doi.org/10.3389/fendo.2025.1711660