Ellagic Acid Alleviates Abnormal Fat Reduction by Activating the RXRβ–PPARγ Pathways in a CT26 Tumour‐Induced Cachexia Mouse Model

Key Points

• Ellagic acid alleviates cancer cachexia-induced fat loss, demonstrating significant therapeutic potential.
• The key metric shows a reduction in abnormal fat reduction associated with cachexia in mouse model.
• Observational analysis in a CT26 tumour-induced cachexia mouse model highlights the RXRβ-PPARγ pathway activation.
• This may enable new treatments for cachexia, given the promising effects observed in the mouse model.

Abstract