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Quercetin induces ferroptosis in ovarian cancer through regulating HSPB1/Notch1 pathway | Synapse
March 3, 2026
Open Access
Quercetin induces ferroptosis in ovarian cancer through regulating HSPB1/Notch1 pathway
BZ
Bo Zhao
Changchun University of Science and Technology
HZ
He Zhu
HQ
Hongfei Qian
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Puntos clave
Quercetin effectively triggers ferroptosis in ovarian cancer cells, promoting tumor cell death.
The study showed a significant increase in ferroptosis markers post-treatment with quercetin.
Analysis of cell viability and signaling pathways highlighted the involvement of HSPB1 and Notch1 in this process.
This finding supports potential quercetin-based therapies for ovarian cancer; further investigation is warranted.
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Zhao et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75d1fc6e9836116a26a36
https://doi.org/https://doi.org/10.1186/s13048-026-01986-2