March 3, 2026Open Access

Adipocyte promotes tumor cell invasion and metastasis via FATP2: a novel cell-cell interaction in papillary thyroid carcinoma

Key Points

Adipocytes promote tumor cell invasion in papillary thyroid carcinoma, implicating a new signaling pathway.
FATP2/TR4 signaling may be a critical target for therapeutic strategies against papillary thyroid carcinoma.
Observational analysis uncovers the role of the microenvironment in cancer progression, highlighting adipocyte interactions.
Targeting the adipocyte/FATP2/TR4 axis may lead to innovative treatments for patients with thyroid carcinoma.

Abstract

Together, these findings suggest that adipocytes in the PTC microenvironment may function via FATP2/TR4 signaling to regulate PTC progression, and targeting this newly identified adipocyte/FATP2/TR4 signaling axis may facilitate the development of novel therapeutic strategies for PTC.

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Discussion

Authors

Lichao Peng

Zeyu Zhang

Hui Ouyang

Journals

Gland Surgery

Actions

Institutions

Central South University

Xiangya Hospital Central South University

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Adipocyte promotes tumor cell invasion and metastasis via FATP2: a novel cell-cell interaction in papillary thyroid carcinoma

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study