Decreased within-default mode network connectivity with accelerated intermittent theta burst stimulation across unipolar and bipolar depression: Candidate transdiagnostic circuit marker for treatment response

Key Points

• Decreased connectivity in the default mode network indicates potential treatment effects of theta burst stimulation.
• Connectivity levels were notably reduced, particularly in patients with unipolar and bipolar depression.
• This analysis employed observed changes following accelerated intermittent theta burst stimulation for treatment.
• Significance highlights the need for further exploration of network markers in managing different depressive disorders.