Exercise alleviates the obesity-related dysfunction of skeletal muscle and heart caused by Akh gene knockdown in Drosophila

Key Points

• Exercise significantly improves heart and skeletal muscle function in Drosophila models influenced by akh gene knockdown.
• The observed enhancements highlight the potential for physical activity to counter obesity-induced dysfunctions.
• This analysis utilized Drosophila models to explore the relationship between exercise and metabolic improvement.
• Findings suggest exercise could be a viable strategy for combating obesity-related heart and muscle disorders.