3D-printed titanium scaffolds coated with a multifunctional photothermal-responsive hydrogel promote osteoporotic bone defect repair

Key Points

• Enhanced bone defect repair occurs with 3D-printed titanium scaffolds coated with a multifunctional hydrogel, promoting tissue regeneration effectively.
• In experiments, bone healing showed significant improvement within a timeframe of eight weeks compared to control scaffolds.
• The approach employed photothermal-responsive hydrogel to facilitate targeted therapy for osteoporotic bone reconstruction.
• This innovative methodology may enable new treatment strategies for bone defects in osteoporotic conditions, highlighting further clinical applications.