Ectonucleotidases: Possible roles in the tumor microenvironment and influence on tumor progression in breast cancer

Key Points

• Tumor progression correlates with ectonucleotidases' activity in the tumor microenvironment, influencing cancer growth.
• Analysis reveals that high ectonucleotidase levels might serve as biomarkers for breast cancer severity over time.
• Observational analysis across various breast cancer models highlights ectonucleotidases' roles in cellular signaling pathways.
• Identifying ectonucleotidases' functions may enable new approaches to manage breast cancer, but clinical validation is needed.