Tumor microenvironment and biomarker innovation in ovarian cancer: mechanistic insights into immune evasion, angiogenesis, and therapeutic resistance

Key Points

• Therapeutic resistance critically affects treatment outcomes in ovarian cancer, and the tumor microenvironment plays a significant role.
• Key mechanisms include immune evasion and angiogenesis, which contribute to the cancer's ability to thrive despite therapy.
• Assessment highlights the importance of innovative biomarkers that could assist in predicting treatment responses effectively.
• Understanding the tumor microenvironment's impact may enable better therapeutic strategies, addressing known limitations in current cancer treatments.