Neoadjuvant chemotherapy versus upfront surgery for perihilar cholangiocarcinoma: a propensity score matching analysis

Key Points

• Neoadjuvant chemotherapy improves treatment outcomes in perihilar cholangiocarcinoma compared to upfront surgery, emphasizing its effectiveness.
• The analysis shows a significant difference in survival rates favoring neoadjuvant chemotherapy based on propensity score matching.
• Utilizing propensity score matching, researchers assessed the comparative effectiveness of two treatment strategies in this challenging cancer type.
• Findings may guide clinical decisions, suggesting neoadjuvant therapy could lead to better patient prognoses in select cases.