Regulation of cell death receptor S-nitrosylation and apoptotic signaling by Sorafenib in hepatoblastoma cells

Key Points

• Sorafenib regulates s-nitrosylation of cell death receptors, impacting apoptotic signaling.
• A significant change in apoptotic markers occurs with treatment, showing 75% increase in cell survival rates.
• Assessment using viable cell counts reveals the influence of sorafenib on hepatoblastoma cell apoptosis.
• These findings highlight sorafenib's potential as a therapeutic option, though further research is needed in clinical settings.