Glucocorticoid-Induced Hyperglycemia in Patients With Cancer: Mechanisms, Clinical Implications, and Management Strategies

Key Points

• Hyperglycemia is a major complication of glucocorticoid treatment in cancer patients, affecting metabolic control.
• Approximately 30% of patients receiving glucocorticoids experience significant hyperglycemia, worsening their condition.
• Analysis of metabolic pathways reveals that glucocorticoids induce insulin resistance, complicating diabetes management.
• This work highlights the need for tailored management strategies for hyperglycemia in cancer patients treated with glucocorticoids.