Does intracranial arterial calcification impact cerebrovascular hemodynamics in the general aging population?
General aging population
Intracranial arterial calcification (exposure)
Cerebrovascular function (MCA pulsatility, cerebrovascular reactivity [CVR], and perforating artery flow velocity and pulsatility) measured by 7T MRIsurrogate
Intracranial arterial calcification is associated with localized increases in MCA pulsatility, suggesting altered cerebrovascular hemodynamics in the aging population.
In this cohort, intracranial arterial calcification was associated with increased MCA pulsatility, suggesting a localized impact on cerebrovascular hemodynamics. Associations with CVR and perforating artery flow velocity and pulsatility did not reach statistical significance. Thus, larger studies are needed to determine whether subtle effects exist.
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Anna Maria Streiber
N.A. Carmen Kuenen
Stanley D.T. Pham
SHILAP Revista de lepidopterología
Cerebral Circulation - Cognition and Behavior
Harvard University
KU Leuven
Erasmus University Rotterdam
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Streiber et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69a75e7ec6e9836116a29262 — DOI: https://doi.org/10.1016/j.cccb.2026.100531