Correlation analysis of gut microbiota and metabolites in gastric cancer patients in plateau areas based on multi-omics technologies

Key Points

• Gastric cancer patients exhibit distinct gut microbiota and metabolite profiles, indicating potential therapeutic targets.
• Bacterial diversity analysis shows significant differences in patients compared to healthy controls, with specific metabolites linked to cancer progression.
• Multi-omics technologies were employed to assess correlations between microbial communities and plasma metabolite levels in gastric cancer cases.
• These findings underscore potential avenues for biomarker development in gastric cancer, warranting further exploration for clinical applicability.