Anticancer activity of Pteris multiaurita gametophytes and sporophytes and its bioactive phytochemicals against the PI3K-AKT-mTOR pathway

Key Points

• Bioactive phytochemicals from Pteris multiaurita exhibit significant anticancer activity against the PI3K-AKT-mTOR pathway.
• The study includes a detailed analysis of both gametophytes and sporophytes sourced from various habitats.
• Bioassays indicated a strong inhibitory effect on cancer cell proliferation and survival metrics.
• These findings may highlight potential natural therapeutic agents for targeting specific cancer pathways.