Case Report: Discordant genetic findings in miscarriage tissue following transfer of euploid embryos

Key Points

• Miscarriage tissue revealed discordant genetic findings, indicating gaps in understanding euploid reliability.
• In two cases, discrepancies pointed to technical constraints associated with preimplantation genetic testing for aneuploidy (PGT-A).
• Analysis followed euploid blastocyst transfer, emphasizing the importance of prenatal diagnosis in such circumstances.
• These findings suggest a need for more comprehensive patient counselling on the risks and technical aspects of PGT-A.

Abstract