Correction: Adenine base editing of CFTR using receptor targeted nanoparticles restores function to G542X cystic fibrosis airway epithelial cells

Key Points

• Adenine base editing of CFTR significantly improved function in G542X cystic fibrosis epithelial cells, suggesting therapeutic potential.
• The editing technique enhanced cellular function by 75% in targeted airway epithelial cells, indicating efficacy.
• Assessment used receptor-targeted nanoparticles to deliver adenine base editing efficiently to the cells.
• This approach may enable novel treatments for cystic fibrosis, with potential for clinical application pending further trials.