Proteomic insights into the dynamic inflammatory and metabolic networks of renal ischemia–reperfusion injury

Key Points

• Dynamic metabolic and inflammatory networks play a vital role in renal ischemia–reperfusion injury, influencing recovery and outcomes.
• Proteomic profiling identified specific biomarkers linked to kidney injury during ischemia and reperfusion, shedding light on underlying mechanisms.
• Assessment used proteomics to analyze inflammatory and metabolic responses in renal tissues following injury across various time points.
• These findings may enable new therapeutic strategies targeting inflammation and metabolism in treating renal ischemia–reperfusion injury.