March 3, 2026Open Access

Cannabis sativa L. roots extract modulates gastrointestinal motility and ameliorates ethanol-induced gastric ulcers in animal models

Key Points

Gastrointestinal motility was positively modulated by cannabis sativa roots extract, showing enhanced movement.
Animal models indicated significant improvement in mitigating gastric ulcers caused by ethanol exposure.
Assessment using gastrointestinal assessments demonstrated the extract's protective qualities against ethanol-induced damage.
This study suggests that cannabis sativa roots may offer a safe, non-psychoactive alternative for treating GI disorders.

Abstract

These findings provide experimental support for the traditional use of C. sativa roots in GI disorders and indicate their potential as a non-psychoactive source of bioactive constituents.

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Cite this study

Sá et al. (Fri,) studied this question.

www.synapsesocial.com/papers/69a75eebc6e9836116a29f09 — DOI: https://doi.org/10.3389/fphar.2026.1743428

Authors

Pedro Guilherme Sousa de Sá

João Gabriel de Souza Rocha

Juliane Maria dos Santos Silva

Journals

Frontiers in Pharmacology

SHILAP Revista de lepidopterología

Actions

Institutions

Universidade Federal Rural de Pernambuco

Universidade Federal do Vale do São Francisco

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Cannabis sativa L. roots extract modulates gastrointestinal motility and ameliorates ethanol-induced gastric ulcers in animal models

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion