Dietary Vitamin B-9 and B-12 Deficiencies Alter Gut Homeostasis in Sprague–Dawley Rats

Key Points

• Alterations in gut homeostasis were observed due to deficiencies in vitamin B-9 and B-12, affecting overall health.
• Rats with vitamin B-9 and B-12 deficiencies showed significant dysbiosis in gut microbiota compared to control groups.
• The assessment utilized Sprague-Dawley rats to study the impact of dietary deficiencies on gut health and microbiota balance.
• Research highlights the necessity of adequate vitamin B-9 and B-12 intake for maintaining intestinal health in rats.