The association of osteoarthritis with the risk of de novo inflammatory arthritis in patients receiving immune checkpoint inhibitors: a retrospective study

Key Points

• Osteoarthritis was more prevalent among patients developing inflammatory arthritis while on immune checkpoint inhibitors, indicating a significant association.
• Among these patients, hand osteoarthritis was the most commonly observed pattern, reinforcing its relevance to inflammatory arthritis development.
• Risk factors for developing inflammatory arthritis included preexisting osteoarthritis, melanoma, and a family history of autoimmune disease.
• This suggests that patients with osteoarthritis may need closer monitoring for inflammatory arthritis when receiving immune checkpoint inhibitors.

Abstract