On-site self-assembly of glycopeptide triggered by bioorthogonal ligation to metabolically labeled bacteria for promoting tissue regeneration in methicillin-resistant Staphylococcus aureus (MRSA)-Infected wounds

Key Points

• Glycopeptide self-assembly promotes tissue regeneration effectively in MRSA-infected models.
• The approach utilizes bioorthogonal ligation, enhancing targeted delivery of therapeutic agents.
• Analysis of metabolically labeled bacteria demonstrates efficient interaction and recovery.
• Potential for novel treatment strategies in managing MRSA infections may be significant.