Diagnostic accuracy of GFAP and S100B as blood-based biomarkers for acute stroke: A systematic review and meta-analysis

Key Points

• GFAP and S100B biomarkers show high diagnostic accuracy for acute stroke.
• The pooled sensitivity for GFAP was 0.85, while S100B had a sensitivity of 0.80.
• Systematic review and meta-analysis of various studies across multiple healthcare settings uncovered these findings.
• This highlights the potential for GFAP and S100B to aid in timely stroke diagnosis, though external validation is necessary.